Are genetic defects, cancer, epilepsy, deafness, blindness, diseases of the brain or even infertility different from the Indian population, compared to other population groups? It is a matter of several researchers in Bangalore, trying to meet its work on the forefront of the field of genomics.

Finding answers could pave the way for early diagnosis, prevention and treatment of various diseases. One of the largest research efforts being done outside the city is in the field of genetics of cancer. Entitled “New targets for the treatment of cancer with the approach of genomics and proteomics” research is a cooperative effort cancer screening, researchers throughout the world “to decipher the genetic changes that occur during the birth and cancer progression.

The leadership of the Indian Institute of Science bio-chemistry professor MRS Rao, the study looks at the genetics of different types of cancer, in order to find likely targets of the drug fight against the disease. One of important discoveries that came near the study is the discovery of a new gene ‘X’ in India patients who can help clinicians days on the development of brain illness.

The Indian Institute of Science Researchers also new types of defects for Indians BRCA1, one of two genes linked with breast cancer, according to the first study ever on gene therapy in India.

“Our data from 14 families suggests a prevalence lower, but the participation of germ-line mutations in the BRCA1 gene among Indian women with breast cancer and a family history of breast cancer,” said Soma Kumaravel Sundaram, Department of Cell Biology and microbiologgy in IISc.

New gaps were also recognized IISc genes in blindness because of glaucoma.

At the Jawaharlal Nehru Center for Advanced Scientific Research, researchers have identified a gene that epilepsy.

The research group headed by Professor Anand Anuranjan is currently in a common effort to digitize epilepsy Indian families concerned for the development of new genes associated with epilepsy.

The group was also the identification of genes and mutations cause deafness and showed that mutations in the gene connexin26 is a major cause of profound deafness in the Indian population.

“Identifying these mutations in infants and children, help in early diagnosis of deafness, so that intervention strategies can be achieved at an early stage, such as rehabilitation,” says Professor Anand.

A large part of gene research in the city is also laying new diagnostic techniques for diseases and disorders of health. The study of breast cancer, for example, a test for early detection of hereditary breast cancers.

Genetics many projects are also on other laboratories, including the city of Nimhans.

Dharamshila Cancer Hospital in Vasundhara in the enclave of Noida, nearly 50 per cent discount on the breast screening for women with a family history of breast cancer. The discount can be enjoyed by 15 August.

Oncologists warn that women whose main ones are suffering from breast cancer are at high risk, the dreaded disease. Dr MS Ganesh, Senior surgical oncologist at the hospital, said: “The risk may go up to seven fold. We must find more and more patients with breast cancer with positive family history. Lack of awareness with respect for the prevention of risks led to the detection of cancer in advanced stage. If women are sufficiently trained on the benefits of prevention periodic surveys on breast cancer, many cases are probably very soon recognized. ”

Women without a family history of breast cancer may also be more than 30 percent off for the screening of breast cancer, cancer of the cervix and ovarian cancer. Dr S. Khanna, director, Dharamshila Cancer Hospital, explains: “The package includes a mammogram two breasts and consultation with specialists cancer. The package will cost Rs 750 instead of the R 1500″.

Mr. Khanna is of the opinion that family members should be a risk factor story focuses on cancer awareness campaign each belonging to each woman to this high-risk group, the notification of their breasts. “The fact that more and more scope on” Premier “of cases of breast cancer arrive at the hospital proves that there is no precaution has been taken in such cases, prevent the development of cancers in a dangerous phase. At that early detection is a must. Adopted, a mother gets breast cancer at 55, his advice is well for a breast screening mammography at age 35. Mother-daughter has just the combination of hospitals for the treatment of breast cancer increases, “she says.

BANGALORE: Are genetic defects, cancer, epilepsy, deafness, blindness, brain disease or even infertility different in the Indian population, compared with other population groups? This is a question many researchers are trying to answer Bangalore their work in the field of genomics-edged.

To find answers, could pave the way for early diagnosis, prevention and treatment of several diseases. A major research effort is outside the city lies in the field of cancer genetics. The title “The new objectives of cancer genomics and proteomics with the approach” of research effort is a collaboration between cancer researchers across the country “to decipher the genetic changes that occur during the birth and progression of cancer. ”

The role of the Indian Institute of Science in bio-chemistry professor MRS Rao, the study is looking at the genetics of different types of cancer in an effort to find perhaps other objectives in the fight against the disease. One of the major discoveries that come from the study is the discovery of a new gene ‘X’ in India patients, doctors, who can help them get an update on the progress of the disease of the brain.

At the Indian Institute of Science, the researchers also new types of errors for the Indians in BRCA1, one of the two breast cancer genes that as a result of the first study ever on gene therapy ‘ India.

“Our data from 14 families suggests a lower prevalence, but the involvement of germline mutation in the BRCA1 gene among Indian women with breast cancer and a family history of breast cancer,” says Soma Sundaram Kumaravel, the Department of Cell Biology and microbiologgy IISc.

New shortcomings were also detected in IISc genes, blindness by glaucoma.
At the Jawaharlal Nehru Center for Advanced Scientific Research, researchers have identified a gene, people with epilepsy.

The research group led by Professor Anuranjan Anand is currently engaged in a large joint effort of epilepsy digitize Indian families involved in the development of novel genes associated with epilepsy.

The group also identifying the genes and mutations causing deafness and has shown that mutations in genes connexin26 is a major cause of profound deafness in the Indian population.

“Identification of these mutations in newborns and children, to come help in the early diagnosis of deafness, so that intervention strategies which can be achieved in an early stage, such as rehabilitation,” explains Professor Anand.

Much of the research on the genes of the city, in fact, there are new diagnostic techniques for diseases and sleep disorders. The study on breast cancer, for example, a test for the early detection of breast cancer is hereditary.

Genetics many projects are also underway in other laboratories, including in the city of Nimhans.